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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b746827eb2453826d92b7d3219be8f46fa263536411f54584d9c6dee6bb2aee4' 
  AND token = 'tguz6Eb4Vl16myqKvFCUVa5R45xI21n8sD9NRbSjkdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}