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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b621f5de166f4fa4d6d039624a08d4f75350775f840872758a0011ef12a3daac' 
  AND token = '2w/dBSKmQDNpJa+iiYH7lZw7nWM1RbK6LOQpAwH2U/I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}