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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46d344fd2c212cf50df8c389b5c48361ceb526aa678cfbc0d780f16e35db118a' 
  AND token = 'BetiL9tss887I7v5gHnMbGokZX3gsGwGmQVzlNyYiBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}