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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '774da1f43f230ea53f874d0410f0d12ee993090b0a66c181c8aaeb0fd5a13af3' 
  AND token = 'oWpiK/0ncZI2VtTVFvnZbpOrHZbjK11ZEQHCLVdjf6E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}