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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df88f89c5def96a4109ef9c4361a5b91dbb6154a408e04987411ae0edddcc831' 
  AND token = '/1CiYHGqI4Dxmvfx62GLjKhOeRK50KyG2iqAmSZ1FI0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}