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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a1197ea3d677c95b799759243c8ec194899c3290487ed6c158c6835f09565f41' 
  AND token = 'm/BU047mXA+AXZ3H8xTUntuaxWsTySCFKUgt0BQpZXU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}