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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8a24b4267f27ec44c6a869373fbddfaeb77aac882503cc7425fad6ab3389997' 
  AND token = 'E8IOW/C+ieVm35uGiZnkgHXEDkjDXY6s2m3gUOo9Kgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}