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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12f69dfc45aacb63b82a902e1a6352df5cc9a8730e1415ea1ccbfd47e8e59fce' 
  AND token = 'hEaMTCWkYvVtvGP+z6VdSRDpRp+2z3EAQ3MOws9BV1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}