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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c81491ba5e9537a13db11264f66e05d3266f9e9b6bc88d207d75c9e2e10539ab' 
  AND token = '2jfrEmyG6FNZmsnr/B7P4moOE4/22G7YFuc2cKBorFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}