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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eb4c46d21f319c8856dc228d2ed7938fe2fa5386b8073453e089da3f06d2beeb' 
  AND token = 'jvTNk4txM4/1GQM+/6H80rPGOH7SfN5UIaV8pYs8MGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}