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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c53c5c0b3ead1429272175e6adfa5db1444b2b7e07e1331520ba4b3da21c2a94' 
  AND token = 'iAtrzKKFf7ecf7Udwpsq61OxgD49u5NYb2Hc0U5RBL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}