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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4185f1165b8f0343e198df8519b3d1aa9fc55782fbccf6e4f945695515c3eb57' 
  AND token = 'BmjzLbLTFGS7xOli7TuAkEIBs4kbmBdG95YqWNe7CxI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}