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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f72474f11b9dd3dd5f0362f3e05c0689f0ad25e56f02e50e7d7220ddd59cd99' 
  AND token = 'Ql+sOouvFiDNM03Z059eafMBzpqO6KcYQdXg+zlDCfc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}