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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e2d92cf04b49907ed40a4e6948cd4deff7f26680d98b55f4e7c45abde26fa0' 
  AND token = 'Virz0IhBP1tuWc0uzVarQ2pYnNCnVmFf+WeI1si6/Ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}