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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51d7eec30dbc7e7b894cf6f20b828d085a615099d611bc39ede9611ae5ce9f5a' 
  AND token = 'pA4y5m8MRLM6A5Tu9CVQapORXI1tnB6td6aVnIcbHS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}