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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f3d24f43bf2c50087bbd7fc05ca0721107dfb435b9f7946e5e8c74a0812318aa' 
  AND token = 'wI2iacxua3cVi2eUNL8tseB/afU8IwFg+zdaYuFhosM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}