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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45781d008ea1887cc67be22057705fc0a24ff37d81a2c7c07812e2705ad07a3d' 
  AND token = '5Lg0PvOcOCQotSSGsN3rbiHAmvg7AxaBynYV+9QH5Q4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}