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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '218a7b8ad57d5b542113fee264a9e37de4bb712c8b069b1a4caba3b3005770f8' 
  AND token = '7K4cQ9Q3c1vU4Q2DRFaTftlPd5XEEfeCQVYJuMmlnGo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}