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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aa2c5a5b22ee8636bfda4bf3aa535658add66ccf3199f3aabd7391c5a4f09ff' 
  AND token = 'QuLWYJOzlFf8wNFaqTPdnzdOCyJ2TBBCoDefvyeUt30=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}