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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fc13bd660b2900e334a21fe37755914af609e96d0c79d74f2fa960f9fcb711ca' 
  AND token = 'mJ275M8YQXC/qVFIO2TIdI98jzjf3+WyqNA27xSoQwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}