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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e2cb550ad30b5aa84c246cfef1fe2a28de532c02770f70b6696233ce4df859b5' 
  AND token = 'CFAaSVYhcH3M1vVGlD0sHa32QcilfhiCODE5g6VDuKI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}