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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a69d241b6802369b9fcb3012239985989c2be05ad7a6b4c11c84bb2ff0fc866' 
  AND token = 'bcvCSxYdMJL0wab27Oor028D9gSVOtoLkJG6ZGJBxFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}