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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '396cf4a88fb18871012b40c7f50ae41ef026f38d236c57b62f1c849fd708a3ac' 
  AND token = 'mEDbydr2VQVdEwbXWe6ozrOgCRpeDH4CvD0sOhB0ivM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}