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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '824f7fd1ac88b935be359aa86fc54ee0dfc35884d2fa26a34a9624a6d9dac7d4' 
  AND token = 'OppEo/9t9sz5zNyaKWHcTVSH4qvlkKANDvq/BLGrlrI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}