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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c22927d35321561f861adda9e0f801229fe165584768b29258e2a1f47c5b7ec3' 
  AND token = 'PIoyaSJ9Gx4QNfDOSC2E/cS85kKaTj89bB4YCBXdCuc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}