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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9cd856b5d7e5c159dd40bc71f401edc18f1c83589ecde5a164b61f8ec038ca4' 
  AND token = 'ujAd1cmT2VRk9Ft66ISqCo1wCfsp3f+UgsyXKJZr/Yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}