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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0eb4857a804119c483788816bff65738bbd979d4df623387e2b05076358db88' 
  AND token = '2+NTIbv+H1LCUd+ApL01yXNB2lJSJKN9IcnCoEq1DpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}