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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '11f68a503b59678eb021efbea8db62d1fc163e77cfe81f5c92e6052cf80daacb' 
  AND token = '6xW/q2W//mTAXgnh99iS/I+4rPlLwf8x3Ao5IaeMshM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}