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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75b3b4debebd87a20744b408b36c6ae38f939c36296b8d3f8db2a3fed2f69f3a' 
  AND token = 'DTE4B8XSNRWfKJo4lO4nF8oo6LWqsSKzQ97TuXq3Ras=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}