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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '815851629bd0405455fac5af53c2c7e9e2981f756453dfd47c751e8cd8def9a9' 
  AND token = 'Mr/9geV5QX5A9pC4vSzFrr6hDcfx60vP/t1FLLmexr0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}