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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '899a4b0912e1857e08c392622e52a98b431c612f991cb8d3217f4e006df17042' 
  AND token = 'WeuCPp1nyjyPRA8W1rABxAwPWJt2JUvwvgnXzpj2Zws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}