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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce6df438a2d715c969be654e62defd7cd0572167bc5133078571d4574e834a9b' 
  AND token = 'w0ZurcxNenYewMmbq8OcI1OI3+drKyMd/AyGZ0ygW/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00059

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}