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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1e2e1f6d74cc7f395b0e98d53b3294fee470f325e2d80080b7a7c4b348207c2' 
  AND token = 'i32ksWxhx1+gn03KUn0uMGHMaTy63qUgXhdOZWL19uk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}