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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16f4748c825788f5864547e751d385099aae74f180ffed6fa7c79254da1f15bf' 
  AND token = '4t7Dp6f1/B2doKdEWphR0zfusvJdYOi1BoWpOhODjjs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}