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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cd3d99b42a203607390476a0dce5d561f45dbc73480c23f4d35f4534719cf50d' 
  AND token = '/CHVaeyT4IA2TzAZ1H5blNLjSVvBO5lOqgQ1VZK5OuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}