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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5aafaa7024ee2b607c0a70c1537e273c4d82500f0682691f209803f95dba0385' 
  AND token = 'IT/4BxsveMh3q/VfCmx9FLga8iwXULybovkd5ci5Ui0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}