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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00c45849d1cb671109c43be0489c25cad34cbe4c616bb1b109af2ff83303081e' 
  AND token = 'G00JkxI2caTKm1AYhlbBpTc3Bg8Yv51hqouYYRtM8zU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}