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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fd16b575d2683c419ca621614ac6ad717695d10b53e95c901bbc074b48603b1f' 
  AND token = 'iYugOi11/mAxMTRxCGVHcwhQIeeAedqTxUYMhh8p5g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}