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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b6580158e0a9b8d2df847665d8d63608f43eb8ac6ab195fa4f0172b2666e2baa' 
  AND token = 'ZQyrdK2iG9c+p39w+jwHMlkAEF3ox8c+Ygp/8CT+NTM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}