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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ccb8d237a0becd3436d0461944d638a659931cb04a15c080e2676e1bcb0affb0' 
  AND token = 'yAVPGd14nOG1UHYVwhnWnV/1d1FvkUn2xWsHb9rmgE4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}