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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74daea45b00460616c441e80b9a1923c27da86ddb27f03a6b0689a3604a31a8c' 
  AND token = 'vLwg5lKziCgzcf/cBlV4tB57RsrtNO5ZK6RJJ4rOjVg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}