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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69a4671d7a58ffc3eac5e5ff440cd9cc03fa256fda45b1b70b50900825ed09be' 
  AND token = 'uL01zfQeDQygLVxE1i0fUcWjugKJOD0Myhifs2gg9cE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}