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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51ac1ece42212fe2846c0351b9797231bb9bcc06af6c0cd69b77e2ab34340a1f' 
  AND token = 'UggG3psNXlyjufuVdxqaDl+EE6oQss8/Jz6SgC0W8t8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}