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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77c50eb3ba7e65072e1a8cd36754e7ea062422c88ec8157d73c7979bbd2393e9' 
  AND token = 'LaBI5hS6M09Fq1xEpDeUHa+CHyYd0e8n5fuCkXbshvw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}