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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14ab47d7393649019b0940796287e8321b5b8b00ec086c246158494bd9b2c49d' 
  AND token = '2tff28VyujhXp+4vefCY3UPIBLk3eHFg58oXGMdOlBY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}