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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '67fa813276c8ecadf9278aada59f239b00a75f4f8e0c1e632a1d0bc0c1a09c02' 
  AND token = 'bk2rn0xEUoUYa8qRH/UgeQG78EDqLeMA+dVHY/iRSOU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}