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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ce8f0ee7ef6be779d99ee9675e2891e8029977c21a4ef8e7f3db66b350824682' 
  AND token = 'bQEbRokmZNz7VrQ+8YPU7HMl1BfuCgQ7MPpScfGTDm0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}