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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5307b7917d1fba5a2d1368d9943b8c3b8393579147056ee5599cf3976d1fe15f' 
  AND token = '5Ls4CBIWj70XSnoLVoq/K4G/pbZ6srcQQtUD0d9EnK0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}