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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a9ec12230d5c57592bca3699ed31afb42ea1e52a81c1f9f944da88cce9e4b0ee' 
  AND token = 'P+NRH+0iMZm2dLLD7rB7km+PxRJ2ToyFDtkjX4nHq+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}