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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a99c5062b49165b8d36b6de06171431105f15217b9f6299373df8114221bb6ac' 
  AND token = 'SsP90b3gS78onMg0OaDnwfvmZQ6bbAjYXBpQp85n0EY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}